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The Simon Research Group at Duke University
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Recent Publications

2006
188. Daniel A. J. Bow, Jennifer L. Perry, John D. Simon, John B. Pritchard, The Impact of Albumin Binding on the Renal Transport of the Fungal Mycotoxin, Ochratoxin A, Journal of Pharmacology and Experimental Theraputics¸ 316, 349-355 (2006)
189. John D. Simon, Michael R. Goldsmith, Lian Hong, Valerie R. Kempf, Laura E. L. McGuckin, Tong Ye, and Gerard Zuber, Spectroscopy and Photoreactivity of Trichochromes: Molecular Components of Pheomelanin, Photochemistry and Photobiology, 82, 318-323 (2006).
190. Tong Ye, Gunay Yurtsever, Martin Fischer, John D. Simon, Warren S. Warren, Imaging Melanin by Two-Photon Absorption Spectroscopy, in Multiphoton Microscopy in the Biomedical Sciences VI, Proceedings of SPIE, 6089, 332-338 (2006).
191. Tong Ye, Lian Hong, Jacob Garguilo, Anna Pawlak, Glenn S. Edwards, Robert J. Nemanich, Tadeusz Sarna and John D. Simon, Photoionization Thresholds of Melanins Obtained Free-Electron Laser Photoelectron Emission Microscopy, Femtosecond Transient Absorption Spectroscopy, and EPR Measurements of Oxygen Photoconsumption, Photochemistry and Photobiology 82, 733-737 (2006).
192. M. Zareba, G. Szewczyk, L. Hong, T. Sarna, J. D. Simon, J. M. Burke, Effects of Photodegradation on the Physical and Antioxidant Properties of Melanosomes Isolated from Retinal Pigment Epithelium, Photochemistry and Photobiology 82, 1024-1029 (2006).
193. Michael C. Pirrung Tong Ye, Zheng Zhou, and John D. Simon, Mechanistic Studies on the Photochemical Deprotection of 3', 5'-Dimethoxybenzoin Esters, Photochemistry and Photobiology 82, 1258-1264 (2006).
194. Lian Hong, John D. Simon, Insight into the Binding of Divalent Cations to Sepia Eumelanin from Infrared Absorption Spectroscopy, Photochemistry and Photobiology 82, 1265-1269 (2006).
195. Jennifer L. Perry, Michael-R. Goldsmith, T. Richard Williams, Kyle Radick, Trine Christenson, Justin Gorham, Melissa A. Pasquinelli, Eric J. Toone, David N. Beratan, and John D. Simon, Binding of Warfarin Influences the Acid-Base Equilibria of H242 in Sudlow Site I of Human Serum Albumin, Photochemistry and Photobiology 82, 1365-1369 (2006).
196. Lian Hong, John D. Simon, Tadeusz Sarna, Melanin Structure and the Potential Functions of Uveal Melanosomes, Pigment Cell Research, 19, 465-466 (2006)
197. William D. Bush, Jacob Garguilo, Fabio A. Zucca, Alberto Albertini, Luigi Zecca, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon, The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and eumelanin surface, Proceedings of the National Academy of Sciences 103, 14785-14789 (2006)
198. Lian Hong, Jacob Garguilo, Laura Anzaldi, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon, Age-Dependent Ionization Potentials of Melanosomes and Lipofuscin Isolated from Human Retinal Pigment Epithelium Cells, Photochemistry and Photobiology 82, 1475-1481 (2006).
2007
199. Weslyn C. Ward, John D. Simon, The differing embryonic origins of retinal and uveal – iris/ciliary body, choroid – melanosomes is mirrored by their phospholipid composition, Pigment Cell Research 20, 61-69 (2007).
200. Jacob Garguilo, Lian Hong, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon, The Surface Oxidation Potential of Eumelanosomes Measured by Free Electron Laser Photoelectron Emission Microscopy, Photochemistry and Photobiology 83, 692-697 (2007).
201. William D. Bush, John D. Simon, Quantification of Ca2+ binding to melanin supports the hypothesis that melanosomes serve a functional role in regulating calcium homeostasis, Pigment Cell Research. 20, 134-139 (2007).
202. Dan Fu, Tong Ye, Thomas E. Matthews, Gunay Yurtsever, Lian Hong, John D. Simon, Warren S. Warran, Two-color excited-state absorption imaging of melanins, in Photonics in Dermatology and Plastic Surgery, Proceedings of SPIE, 6424, 542402 (2007).
203. Lian Hong, John D. Simon, Current Understanding of the binding sites, capacity, affinity, and biological significance of metals in melanin, Invited feature article, Journal of Physical Chemistry B, 111, 7938-7947 (2007).
204. Weslyn C. Ward, Ziqiang Guan, Fabio A. Zucca, Alberto Albertini, Reza Korestani, Luigi Zecca, Christian R. Raetz, and John D. Simon, Quantification of dolichols and the identification of dolichoic acid in the substantia nigra of the human brain, Journal of Lipid Research, 48, 1457 – 1462 (2007).
2008
205. Lian Hong, Lanying Q. Hatcher, William D. Bush, John D. Simon, Determining Thermodynamics Parameters from Isothermal Calorimetric Isotherms of the Binding of Macromolecule to Metal Cations Originally Chelated by a Weak Ligand, Journal of Physical Chemistry, a special issue honoring James T. Hynes, Web Release Date: 21-Nov-2007; (Article) DOI: 10.1021/jp075747r.
206. Tong Ye, Anna Pawlak, Tadeusz Sarna. John D. Simon, Different Molecular Constituents in Pheomelanin are Responsible for the Emission, Transient Absorption and Oxygen Photoconsumption, Photochemistry and Photobiology.
207. Tong Ye, Dan Fu, Thomas E. Matthews, Lian Hong, John D. Simon, Warren S. Warren, Two-photon absorption and transient photothermal imaging of pigments in tissues, Proceedings of SPIE.
Submitted
208. Weslyn C. Ward, Erin C, Lamb, David Gooden, Xin Chen, David J. Burinsky, John D. Simon, Quantification of Naturally Occurring Pyrrole Acids in Melanosomes, Photochemistry and Photobiology.
209. Dan-Ning Hu, John D. Simon, Tadeusz Sarna, Role of Ocular Melanin in Ophthalmic Physiology and Pathology, Photochemistry and Photobiology..
210. Lanying Q. Hatcher, Lian Hong, William D. Bush, and John D. Simon, Quantification of the Binding Constant of Copper(II) to the Amyloid-Beta Peptide, Journal of Physical Chemistry B.
211. David Sulzer, Eugene Mosharov, Fabio A. Zucca, John D. Simon and Luigi Zecca, Neuromelanin, lipofuscin, and ceroid as neuronal autophagic responses during aging and disease, Journal of Neurochemistry.
212. Senli Guo, Lian Hong, John D. Simon, Boris B. Akhremitchev, Surface Elastic Properties of Human Retinal Pigment Epithelium Melanosomes, Photochemistry and Photobiology. Derek Bush, Fabio A. Zucca, Alberto Albertini, Robert J. Nemanich, Glenn S. Edwards, Luigi Zecca, John D. Simon, Neuromelanins Isolated from Different Regions of the Human Brain Exhibit Common Surface Photoionization Thresholds, Photochemistry and Photobiology, Symposium-in-Print on melanins.