Shaw Publications
2007 2006 2005 2004
2003
2002
2001
2000
1999
1998
1997
1996
1995-93
1992-90
Previous
2008
- Wennefors, C.K., Dobrikov, M.I., Xu, Z., Li, P, Shaw, B.R.
"Stereospecificity, Substrate, and Inhibitory Properties of NucleosideDiphosphate Analogs for Creatine and Pyruvate Kinases"
Bioorganic Chemistry (2008) (accepted)
2007
- Khan, Shoeb I.; Shaw, Barbara Ramsay. "Efficient Synthesis
Of Thymidine Boranophosphoramidates Conjugated With Amino Acids."
Nucleosides, Nucleotides & Nucleic Acids, 26(6-7), 621-623 (2007) PDF
- Liu, Hongyan; Hashmi, Syed N.; Shaw, Barbara Ramsay.
"Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an
H-Phosphonate Approach." Nucleosides, Nucleotides &
Nucleic Acids. 26(10-12), 1455-1457 (2007) PDF
- Li, Ping; Sergueeva, Zinaida A.; Dobrikov, Mikhail; Shaw, Barbara
Ramsay. "Nucleoside and Oligonucleoside Boranophosphates:
Chemistry and Properties." Chemical Reviews 107(11),
4746-4796. (2007). PDF
TOP
2006
- Hall, Allison H. S.; Wan, Jing; Spesock, April; Sergueeva,
Zinaida; Shaw, Barbara Ramsay; Alexander, Kenneth A. "High
potency silencing by single-stranded boranophosphate siRNA."
Nucleic Acids Research, 34(9), 2773-2781.(2006) PDF
2005
- Li, P. and Shaw, B.R. "Synthesis of Nucleoside
Boranophosphoramidate Prodrugs Conjugated with Amino Acids". J. Organic
Chem. 70, 2171-2183 (2005) PDF
- Summers, J.S., Base, K., Boukhalfa, H., Payne, J.E., Shaw,
B.R., and Crumbliss, A.L."Use of Phosphorus Ligand NMR Probes to
Investigate Electronic and Second-Sphere Solvent Effects in Ligand
Substitution Reactions at Manganese(II) and Manganese(III)." Inorganic Chemistry. 44(10), 3405-3411 (2005) PDF
- Li P., and Shaw, B.R. "Model Synthesis of Nucleoside Boranophosphoramidate with Amino Acid for Prodrug
Purpose." Nucleosides, Nucleotides & Nucleic Acids, 24(5-7), 675-678 (2005) PDF
- Wan, J., and Shaw, B.R. "Incorporation of Ribonucleoside
5'-(±-P-Borano)triphosphates into a 20-mer RNA by T7 RNA
Polymerase."Nucleosides, Nucleotides & Nucleic Acids, 24(5-7), 943-946 (2005) PDF
- Wang, J.X. and Shaw, B.R."Synthesis of
5-(1-Propynyl)-2'-deoxyuridine 5'-(alpha-P-Borano)triphosphate and
KineticCharacterization as a Substrate for MMLV Reverse Transcriptase."
Nucleosides, Nucleotides& Nucleic Acids, 24(5-7), 947-950 (2005) PDF
- Wang, J.X., Sergueev, D.S., and Shaw, B.R. "The Effect of a
Single Boranophosphate Substitution with Defined Configuration on the
Thermal Stability and Conformation of a DNA Duplex". Nucleosides,
Nucleotides & NucleicAcids, 24(5-7), 951-955 (2005) PDF
- Dobrikov, M.I. and Shaw, B.R. "Affinity of
(±-P-borano)-NTP Analogs to Rabbit Muscle Pyruvate Kinase."
Nucleosides, Nucleotides & Nucleic Acids, 24(5-7), 983-987 (2005) PDF
- Khan, S.I., Dobrikov, M.I., and Shaw, B.R. "Synthesis of
5-Ethynyl-2'-deoxyuridine-5'-boranomonophosphate as a Potential
Thymidylate Synthase Inhibitor." Nucleosides, Nucleotides & Nucleic Acids, 24(5-7), 1047-1049 (2005) PDF
- Li, P., Xu, Z., Liu, H., Wennefors, C.K., Dobrikov,
M.I., Ludwig, J., and Shaw, B.R."Synthesis of
alpha-P-Modified Nucleoside Diphosphates with Ethylenediamine" J. Amer. Chem. Soc. 127(48);
16782-16783. PDF
TOP
2004
- Hall, A. H. S.; Wan, J.; Shaughnessy, E. E.; Shaw, B. R.; and Alexander, K. A.
"RNA Interference Using Boranophosphate siRNAs: Structure-Activity Relationships"
Nucleic Acids Research 32, 5991-6000 (2004).
PDF
- Li, P. and Shaw, B. R.
"Convenient Synthesis of Nucleoside Borane Diphosphate Analogues: Deoxy- and Ribonucleoside 5'-P-alpha-Boranodiphosphates" Journal of Organic Chemistry 69,
7051-57 (2004). PDF
- Shaw, B.R., Dobrikov, M., Sergueev, D., Sergueeva,
Z., Wan, J., Wang, X., He, K., Porter, K., Li,
P and Lin, J."Reading, Writing, and Modulating Genetic Information
with Boranophosphate Mimics of Nucleotides, DNA, and RNA.", in
Therapeutic Oligonucleotides: Antisense, RNAi, Triple Helix, DNA
Decoys, and DNA Chips, ed Y.S. Cho-Chung, A. M. Gewirtz, and C. A.
Stein.Annals of the New York Academy of Sciences, Volume 1002, 12-29, (2004).
TOP
2003
- Dobrikov, M. I.; Grady, K. M.; and Shaw, B. R.
"Introduction of the alpha-P-Borano-Group
into Deoxynucleoside Triphosphates Increases their Selectivity to HIV-1
Reverse Transcriptase Relative to DNA Polymerases" Nucleosides Nucleotides & Nucleic Acids 22(3), 275-82 (2003).
PDF
- Li, P.; Dobrikov, M. I.; Liu, H.; and Shaw, B. R.
"Synthesis of Acyclothymidine Triphosphate and alpha-P-Borano-triphosphate and their Substrate
Properties with Retroviral Reverse Transcriptase" Organic Letters 5,
2401-03 (2003). PDF
- Li, P.; and Shaw, B. R.
"One-Pot Synthesis of an AZT Boranophosphate Conjugated with Tyrosine: A Potential Prodrug Candidate"
Nucleosides Nucleotides & Nucleic Acids 22(5-8), 699-701 (2003).
PDF
- Wang, X.; Dobrikov, M. I.; Sergueev, D.; and Shaw, B. R.
"RNase H Activation by Stereoregular Boranophosphate Oligonucleotide"
Nucleosides Nucleotides & Nucleic Acids 22(5-8), 1151-53 (2003).
PDF
- Dobrikov, M. I.; Sergueev, Z.; and Shaw, B. R.
"Incorporation of (alpha-P-Borano)-2'-3'-dideoxycytidine 5'-Triphosphate into DNA by Drug-Resistant MMLV Reverse Transcriptase and Taq DNA Polymerase"
Nucleosides Nucleotides & Nucleic Acids 22(5-8), 1651-55 (2003).
PDF
- Shaw, B. R.; Dobrikov, M. I.; Sergueev, D.; Sergueev, Z.; Wan, J.; Wang, X.; He, K.; Porter, K.; Li, P.; and Lin, J.-L.
"Reading, Writing, and Modulating Genetic Information with Boranophosphate Mimics of Nucleotides, DNA, and RNA"
in Therapeutic Oligonucleotides: Antisense, RNAi, Triple Helix, DNA Decoys, and DNA Chips ed Y.S. Cho-Chung, A. M. Gewirtz, and C. A. Stein.
Annals of the New York Academy of Sciences 1002, 12-29 (2003).
PDF
TOP
2002
- Li, P.; and Shaw, B. R. "Synthesis of Nucleoside 3', 5'-Cyclic Boranophosphorothioate,
a New Type of Cyclic Nucleotide" Chemical Communications, 2890-91
(2002). PDF
- Astriab-Fisher, A.; Sergueev, D.; Fisher, M.; Shaw, B. R.; and Juliano,
R. L. "Conjugates of Antisense Oligonucleotides with the Tat and Antennapedia
Cell-Penetrating Peptides: Effects on Cellular Uptake, Binding to Target Sequences,
and Biologic Actions" Pharmaceutical Research 19, 744-54
(2002). PDF
- Crow, S. D. G.; Bailly, C.; Garbay-Jaureguiberry, C.; Roques, B.; Shaw,
B. R.; and Waring, M. J. "DNA Sequence Recognition by the Antitumor Drug
Ditercalinium" Biochemistry 41, 8672-82 (2002). PDF
- Astriad-Fisher, A.; Ye, D. J.; Sergueev, D. S.; Fisher, M. H.; Shaw, B.
R.; and Juliano, R. L. "Evaluating the Specificity of Antisense Oligonucleotide
Conjugates - a DNA Array Analysis" Journal of Biological Chemistry
277, 22980-84 (2002). PDF
- Li, P.; and Shaw, B. R. "Synthesis of Prodrug Candidates: Conjugates
of Amino Acid with Nucleoside Boranophosphate" Organic Letters
4, 2009-12 (2002). PDF
- Lato, S. M.; Ozerova, N. D. S.; He, K. Z.; Sergueeva, Z.; Shaw, B. R.; and
Burke, D. H. "Boron-Containing Aptamers to ATP" Nucleic Acids
Research 30, 1401-07 (2002). PDF
- Shaw, B. R.; Wan, J.; Wang. X.; Dobrikov, M.; He, K.; Porter, K.; Lin, J. L.; Rait, V.; Sergueev, D.; and Sergueeva, Z.
"Reading and Writing Genetic Information with Boranophosphate (Borane
Phosphate) Mimics of Nucleotides, DNA and RNA" in Chemistry of Nucleic
Acid Components, ed. Z. Tocik and M. Hocek, Academy of Sciences of the
Czeck Republic, Prague, Collection Symposium Series (Vol. 5) 169-80
(2002).
TOP
2001
- Summers, J. S.; Hoogstraten, C. G.; Britt, R. D.; Base, K.; Shaw,
B. R.; Ribeiro, A. A.; and Crumbliss, A. L. "P-31 NMR probes of
chemical dynamics: Paramagnetic relaxation enhancement of the H-1 and
P-31 NMR resonances of methyl phosphite and methylethyl phosphate
anions by selected metal complexes" Inorganic Chemistry 40, 6547-54 (2001).
PDF
- Lin, J. L.; and Shaw, B. R. "Synthesis of new classes of boron-containing nucleotides" Nucleosides Nucleotides & Nucleic Acids 20, 587-96 (2001).
PDF
- Sergueev, D. S.; Sergueeva, Z. A.; and Shaw, B. R. "Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection" Nucleosides Nucleotides & Nucleic Acids 20, 789-95 (2001).
PDF
- Sergueeva, Z. A.; Sergueev, D. S.; and Shaw, B. R. "Borane-amine
complexes - Versatile reagents in the chemistry of nucleic acids and
their analogs" Nucleosides Nucleotides & Nucleic Acids 20, 941-45 (2001).
PDF
- Lin, J. L.; Porter, K. W.; and Shaw, B. R. "Synthesis and
properties of novel triphosphate analogues: Ribonucleoside and
deoxyribonucleoside (alpha-P-borano, alpha-P-thio)triphosphates" Nucleosides Nucleotides & Nucleic Acids 20, 1019-23 (2001).
PDF
- Lin, J. L.; and Shaw, B. R. "Synthesis of a novel nucleic acid mimic:
P-boranomethylphosphonate" Nucleosides Nucleotides & Nucleic Acids
20, 1325-28 (2001). PDF
- Summers, J. S.; and Shaw, B. R. "Boranophosphates as mimics of natural phosphodiesters in DNA" Current Medicinal Chemistry 8, 1147-55 (2001).
Abstract
- Lin, J. L.; He, K. Z.; and Shaw, B. R. "Novel 3', 5'-cyclic nucleotide
analogue: Adenosine 3', 5'-cyclic boranomonophosphate" Organic Letters
3, 795-97 (2001). PDF
- He, K. Z.; and Shaw, B. R. "Synthesis and separation of diastereomers
of uridine 2', 3'-cyclic boranophosphate" Bioorganic & Medicinal
Chemistry Letters 11, 615-17 (2001). PDF
TOP
2000
- Lin, J. L.; and Shaw, B. R. "Synthesis of a novel triphosphate analogue:
nucleoside alpha-P-borano, alpha-P-thiotriphosphate" Chemical
Communications, 2115-16 (2000). PDF
- Lin, J. L.; and Shaw, B. R. "Synthesis of a boron analogue of glucose-conjugated
nucleoside diphosphate: nucleoside alpha-P-boranodiphosphoglucose" Tetrahedron
Letters 41, 6701-04 (2000). PDF
- Sergueeva, Z. A.; Sergueev, D. S.; Ribeiro, A. A.; Summers, J. S.; and Shaw,
B. R. "Individual isomers of dinucleoside boranophosphates as synthons
for incorporation into oligonucleotides: Synthesis and configurational assignment"
Helvetica Chimica Acta 83, 1377-91 (2000). PDF
- Lin, J. L.; He, K. Z.; and Shaw, B. R. "Synthesis of boron-containing
ADP and GDP analogues: Nucleoside 5'-(P-alpha-boranodiphosphates)"
Helvetica Chimica Acta 83, 1392-97 (2000). PDF
- Shaw, B. Ramsay; D. S. Sergueev, Z. A. Sergueeva, K. W. Porter, V. K. Rait,
J. S. Summers, K. He, and J.-L. Lin "Boronated Nucleic Acid Mimics: Antisense
and DNA Chip Applications" Antisense and Nucleic Acid Drug Development
10, 131-132 (2000).
- Astriab-Fisher, A.; Sergueev, D. S.; Fisher, M.; Shaw, B. R.; and Juliano,
R. L. "Antisense inhibition of P-glycoprotein expression using
peptide-oligonucleotide conjugates" Biochemical Pharmacology
60, 83-90 (2000). PDF
- Sergueeva, Z. A.; Sergueev, D. S.; and Shaw, B. R. "Rapid and selective
reduction of amide group by borane-amine complexes in acyl protected nucleosides"
Nucleosides Nucleotides & Nucleic Acids 19, 275-82 (2000).
Abstract
- Shaw, B. R.; Sergueev, D.; He, K. Z.; Porter, K.; Summers, J.; Sergueeva,
Z.; and Rait, V. "Boranophosphate Backbone: A Mimic of Phosphodiesters, Phosphorothioates,
and Methylphosphonates" Methods in Enzymology: Antisense Technology
313, 226-57 (2000). Abstract
- Hughes, J.; Astriab, A.; Yoo, H.; Alahari, S.; Liang, E.; Sergueev, D.;
Shaw, B. R.; and Juliano, R. L. "In vitro Transport and Delivery of Antisense
Oligonucleotides" Methods in Enzymology: Antisense Technology 313,
342-58 (2000). Abstract
- Sergueeva, Z. A.; D. S. Sergueev, A. A. Ribeiro, J. S. Summers, B. Ramsay
Shaw "Individual Isomers of Dinucleoside Boranophosphates as Synthons for
Incorporation into Oligonucleotides. Synthesis and Configurational Assignment"
in Perspectives in Nucleoside and Nucleic Acid Chemistry, eds. M. Volkan
Kisakurek and Helmut Rosemeyer, Verlag Helvetica Chimica Acta, Zurich pp.
109-124 (2000).
- Lin, J. L.; K. He, and B. Ramsay Shaw "Synthesis of Boron-containing ADP
and GDP Analogues: Nucleoside 5'-(alpha-P-Borano)diphosphates" in Perspectives
in Nucleoside and Nucleic Acid Chemistry, eds. M. Volkan Kisakurek and
Helmut Rosemeyer, Verlag Helvetica Chimica Acta, Zurich pp. 125-130 (2000).
TOP
1999
- Rait, V.; Sergueev, D.; Summers, J.; He, K. Z.; Huang, F. Q.;
Krzyzanowska, B.; and Shaw, B. R. "Boranopbosphate nucleic acids - A
versatile DNA backbone" Nucleosides & Nucleotides 18, 1379-80 (1999).
Abstract
- Lin, J. L.; and Shaw, B. R. "Synthesis and properties of a novel phosphodiester analogue, nucleoside boranophosphorothioate" Chemical Communications, 1517-18 (1999).
PDF
- He, K. Z.; Sergueev, D. S.; Sergueeva, Z. A.; and Shaw, B. R. "Synthesis
of diuridine 3', 5'-boranophosphate: H-phosphonate approach" Tetrahedron
Letters 40, 4601-04 (1999). PDF
- He, K. Z.; Porter, K. W.; Hasan, A.; Briley, J. D.; and Shaw, B. R. "Synthesis
of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates,
their incorporation into DNA and effects on exonuclease" Nucleic Acids
Research 27, 1788-94 (1999). PDF
- Rait, V. K.; and Shaw, B. R. "Boranophosphates support the RNase H cleavage of polyribonucleotides" Antisense & Nucleic Acid Drug Development 9, 53-60 (1999).
Abstract
- Sergueeva, Z. A.; Sergueev, D. S.; and Shaw, B. R. "Synthesis of dithymidine
boranophosphates via stereospecific boronation of H-phosphonate diesters
and assignment of their configuration" Tetrahedron Letters
40, 2041-44 (1999). PDF
- He, K.; and Shaw, B. R. "Diastereomers of 5'-O-adenosyl 3'-O-uridyl
Boranophosphate [Up(BH3)A]: Synthesis and Nuclease Resistant Property" in
Nucleic Acids Symposium Series No. 41, Oxford Univ. Press, Oxford,
UK pp. 99-100 (1999).
TOP
1998
- Sergueev, D. S.; and Shaw, B. R. "H-phosphonate approach for solid-phase
synthesis of oligodeoxyribonucleoside boranophosphates and their characterization"
Journal of the American Chemical Society 120, 9417-27 (1998).
PDF
- He, K. H.; Hasan, A.; Krzyzanowska, B.; and Shaw, B. R. "Synthesis
and separation of diastereomers of ribonucleoside 5'-(alpha-P-borano)triphosphates"
Journal of Organic Chemistry 63, 5769-73 (1998). PDF
- Summers, J. S.; Roe, D.; Boyle, P. D.; Colvin, M.; and Shaw, B.
R. "Structural studies of a borane-modified phosphate diester linkage:
Ab initio calculations on the dimethylboranophosphate anion and the
single-crystal X-ray structure of its diisopropylammonium salt" Inorganic Chemistry 37, 4158-59 (1998).
PDF
- Krzyzanowska, B. K.; He, K. Z.; Hasan, A.; and Shaw, B. R. "A convenient
synthesis of 2'-deoxyribonucleoside 5'-(alpha-P-borano)triphosphates"
Tetrahedron 54, 5119-28 (1998). PDF
TOP
1997
- Hasan, A.; Tomasz, J.; and Shaw, B. R. "Studies on base-boronated oligonucleotides.
2 (1). Incompatibility of DMT and cyanoborane groups during oligonucleotide
synthesis" Bioconjugate Chemistry 8, 813-18 (1997). PDF
- Sergueev, D.; Hasan, A.; Ramaswamy, M.; and Shaw, B. R. "Boranophosphate
oligonucleotides: New synthetic approaches" Nucleosides & Nucleotides
16, 1533-38 (1997).
- Hasan, A.; and Shaw, B. R. "Oligonucleotides containing N7-cyanoborane-2'-deoxyguanosine"
Nucleosides & Nucleotides 16, 1539-42 (1997).
- Li, H.; Huang, F. Q.; and Shaw, B. R. "Conformational studies of dithymidine
boranomonophosphate diastereoisomers" Bioorganic & Medicinal Chemistry
5, 787-95 (1997). PDF
- Porter, K. W.; Briley, J. D.; and Shaw, B. R. "Direct PCR sequencing
with boronated nucleotides" Nucleic Acids Research 25,
1611-17 (1997). PDF
- He, K.; Hasan, A.; and Shaw, B. R. "The Synthesis
of Ribonucleoside 5'-O-(alpha-P-Boranotriphosphates), Separation of
Diastereomers and Incorporation by RNA Polymerases" in Nucleic Acids
Symposium Series 36, Oxford University Press, p. 159 (1997)
TOP
1996
- Gao, Q.; Sood, A.; Shaw, B. R.; and Williams, L. D. "2'-deoxycytidine-N3-cyanoborane"
Acta Crystallographica Section C - Crystal Structure Communications
52, 1823-25 (1996).
- Singh, P.; Zottola, M.; Huang, S. Q.; Shaw, B. R.; and Pedersen, L. G. "2'-deoxycytidine-N(3)-cyanoborane
monohydrate" Acta Crystallographica Section C - Crystal Structure
Communications 52, 693-96 (1996).
- Peng, W.; and Shaw, B. R. "Accelerated deamination of cytosine residues
in UV-induced cyclobutane pyrimidine dimers leads to CC->TT transitions"
Biochemistry 35, 10172-81 (1996). PDF
- Merchant, K.; Chen, H.; Gonzalez, T. C.; Keefer, L. K.; and Shaw, B. R.
"Deamination of single-stranded DNA cytosine residues in aerobic nitric
oxide solution at micromolar total NO exposures" Chemical Research
in Toxicology 9, 891-96 (1996). PDF
- Li, H.; Hardin, C.; and Shaw, B. R. "Hydrolysis of thymidine boranomonophosphate
and stepwise deuterium substitution of the borane hydrogens. P-31 and B-11
NMR studies" Journal of the American Chemical Society 118,
6606-14 (1996). PDF
- Hasan, A.; Li, H.; Tomasz, J.; and Shaw, B. R. "Base-boronated dinucleotides:
Synthesis and effect of N7-cyanoborane substitution on the base protons"
Nucleic Acids Research 24, 2150-57 (1996). PDF
TOP
1995-1993
- Li, H.; Porter, K.; Huang, F. Q.; and Shaw, B. R. "Boron-Containing
Oligodeoxyribonucleotide 14mer Duplexes - Enzymatic-Synthesis and Melting
Studies" Nucleic Acids Research 23, 4495-501 (1995). Abstract
- Porter, K. W.; Tomasz, J.; Huang, F. Q.; Sood, A.; and Shaw, B. R. "N7-Cyanoborane-2'-Deoxyguanosine
5'-Triphosphate Is a Good Substrate for DNA-Polymerase" Biochemistry
34, 11963-69 (1995). PDF
- Rajendran, K. G.; Burnham, B. S.; Chen, S. Y.; Sood, A.; Spielvogel, B.
F.; Shaw, B. R.; and Hall, I. H. "Anti-Inflammatory and Anti-Osteoporotic
Activities of Base-Boronated Nucleosides and Phosphate-Boronated Nucleotides
in Rodents" Journal of Pharmaceutical Sciences 83, 1391-95
(1994). Abstract
- Chen, H.; and Shaw, B. R. "Bisulfite Induces Tandem Double CC-TT Mutations
in Double-Stranded DNA. 2. Kinetics of Cytosine Deamination" Biochemistry
33, 4121-29 (1994). PDF
- Zottola, M.; L. G. Pedersen, P. Singh and B. Ramsay Shaw "Borohydrides as
Novel Hydrogen-Bond Acceptors" in Modeling the Hydrogen Bond, Proceedings
from American Chemical Society Symposia Series No. 569, Computers in Chemistry,
ed. D. A. Smith, 277-85 (1994).
- Spielvogel, B. F.; A. Sood, B. Ramsay Shaw and I. H. Hall "Synthesis of
Boron Analogues of Biomolecules as Potential New Pharmaceuticals" in Current
Topics in the Chemistry of Boron, Proceedings of the Eighth International
Meeting on Boron Chemistry, ed. G. W. Kabalka, The Royal Society of Chemistry,
Cambridge, U.K. 193-98 (1994).
- Burnham, B. S.; S. Y. Chen, K.G. Rajendran, A. Sood, B. F. Spielvogel, B.
Ramsay Shaw, and I. H. Hall "The Synthesis of Amine-Borane Adducts of Cyclohexylamine,
Toluidine, and 3'-Amino-dideoxynucleosides and Evaluation of their Pharmacological
Activity" in Current Topics in the Chemistry of Boron, Proceedings of the
Eighth International Meeting on Boron Chemistry, ed. G. W. Kabalka, The
Royal Society of Chemistry, Cambridge, U.K. 189-92 (1994).
- Shaw, B. R. "Induced Deamination of Cytosine: Effect of Secondary Structure
and Other Factors" in Structural Biology: The State of the Art 2,
eds. Sarma, R. H. and Sarma, M. H., Adenine Press, NY 367-78 (1994)
- Moyer, R.; Briley, D.; Johnsen, A.; Stewart, U.; and Shaw, B. R. "Echinomycin,
a Bis-Intercalating Agent, Induces C-T Mutations Via Cytosine Deamination"
Mutation Research 288, 291-300 (1993). PDF
- Frederico, L. A.; Kunkel, T. A.; and Shaw, B. R. "Cytosine Deamination
in Mismatched Base-Pairs" Biochemistry 32, 6523-30 (1993).
PDF
- Hall, I. H.; Burnham, B. S.; Rajendran, K. G.; Chen, S. Y.; Sood, A.; Spielvogel,
B. F.; and Shaw, B. R. "Hypolipidemic Activity of Boronated Nucleosides
and Nucleotides in Rodents" Biomedicine & Pharmacotherapy
47, 79-87 (1993). Abstract
- Chen, H.; and Shaw, B. R. "Kinetics of Bisulfite-Induced Cytosine Deamination
in Single-Stranded-DNA" Biochemistry 32, 3535-39 (1993).
PDF
- Shaw, B. R.; J. Madison, A. Sood, and B. F. Spielvogel "Oligonucleoside
Boranophosphate (Borane Phosphonate) Oligomers" in Protocols for Oligonucleotides
and Analogs: Synthesis and Properties, ed. S. Agrawal, Methods in Molecular
Biology Series 20, 225-43 (1993). Abstract
- Spielvogel, B. F.; A. Sood, W. Powell, J. Tomasz, K. Porter and B. Ramsay
Shaw "Chemical and Enzymatic Incorporation of Boron into DNA" in Advances
in Neutron Capture Therapy, eds. R. F. Barth and A. H. Soloway, Plenum
Press, NY pp. 389-393 (1993).
- Spielvogel, B. F.; A. Sood, J. Tomasz, B. R. Shaw, S. Karthikeyan, W. Powell,
B. Laster, R. M. Brugger, and J. Coderre "Boronated Peptides and Nucleic Acid
Compounds for NCT" in Advances in Neutron Capture Therapy, eds. R.
F. Barth and A. H. Soloway, Plenum Press, NY pp. 361-365 (1993).
TOP
1992-1990
- Sood, A.; Shaw, B. R.; Spielvogel, B. F.; Hall, E. S.; Chi, L. K.; and Hall,
I. H. "The Synthesis and Antineoplastic Activity of N2-Isobutyryl-2'-Deoxyguanosine-N7-Cyanoborane
Derivatives" Archiv der Pharmazie 47, 833-38 (1992). Abstract
- Tomasz, J.; Shaw, B. R.; Porter, K.; Spielvogel, B. F.; and Sood, A. "Boron-Containing
Nucleic-Acids. 3. 5'-P-Borane-Substituted Thymidine Monophosphate and
Triphosphate" Angewandte Chemie-International Edition in English
31, 1373-75 (1992).
- Hall, I. H.; Hall, E. S.; Chi, L. K.; Shaw, B. R.; Sood, A.; and Spielvogel,
B. F. "Antineoplastic Activity of Boron-Containing Thymidine Nucleosides
in Tmolt(3) Leukemic-Cells" Anticancer Research 12, 1091-98
(1992). Abstract
- MacPhail, R. A.; Williams, L. D.; Jones, D. A.; and Shaw, B. R. "Variable
Temperature Infrared-Spectroscopy of Cytosine-Guanine Base-Pairs - Tautomerism
Versus Polarization" Journal of Biomolecular Structure & Dynamics
9, 881-98 (1992). Abstract
- Sood, A.; Spielvogel, B. F.; Shaw, B. R.; Carlton, L. D.; Burnham, B. S.;
Hall, E. S.; and Hall, I. H. "The Synthesis and Antineoplastic Activity
of 2'-Deoxy-Nucleoside-Cyanoboranes in Murine and Human Culture Cells"
Anticancer Research 12, 335-43 (1992). Abstract
- Spielvogel, B. F.; A. Sood, B. Ramsay Shaw, I. H. Hall, R. G. Fairchild,
B. H. Laster and C. Gordon "Boron Containing Nucleic Acids" in Progress
in Neutron Capture Therapy for Cancer, ed. B. J. Allen, Plenum Press,
NY pp. 211-213 (1992).
- Spielvogel, B. F.; Sood, A.; Shaw, B. R.; and Hall, I. H. "From Boron
Analogs of Amino Acids to Boronated DNA - Potential New Pharmaceuticals and
Neutron-Capture Agents" Pure and Applied Chemistry 63,
415-18 (1991).
- Sood, A.; Shaw, B. R.; and Spielvogel, B. F. "Boron-Containing
Nucleic-Acids .2. Synthesis of Oligodeoxynucleoside Boranophosphates" Journal of the American Chemical Society 112, 9000-01 (1990).
PDF
- Frederico, L. A.; Kunkel, T. A.; and Shaw, B. R. "A Sensitive
Genetic Assay for the Detection of Cytosine Deamination - Determination
of Rate Constants and the Activation-Energy" Biochemistry 29, 2532-37 (1990).
PDF
- Williams, L. D.; Williams, N. G.; and Shaw, B. R. "In a Model C-G Base Pair, One Amino Group Rotates and the Other Does Not" Journal of the American Chemical Society 112, 829-33 (1990).
PDF
- Sood, A.; Spielvogel, B. F.; and Shaw, B. R. "Boron-Containing
Nucleic-Acids - Synthesis of Cyanoborane Adducts of
2'-Deoxynucleosides" Journal of the American Chemical Society 111, 9234-35 (1989).
PDF
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1989
& Before
- Sowers, Lawrence C.; Sedwick, W. David; Shaw, Barbara Ramsay.
"Hydrolysis of N3-methyl-2'-deoxycytidine: model compound for
reactivity of protonated cytosine residues in DNA." Mutation Research,
Fundamental and Molecular Mechanisms of Mutagenesis,
215(1), 131-8.(1989) PDF
- Sood, Anup; Shaw, Barbara Ramsay; Spielvogel, Bernard F.
"Boron-containing nucleic acids. Synthesis of cyanoborane adducts
of 2'-deoxynucleosides." Journal of the American Chemical
Society, 111(26), 9234-5. (1989) PDF
- Williams, Nidhi Gupta; Williams, Loren Dean; Shaw, Barbara
Ramsay. "Dimers, trimers, and tetramers of cytosine with
guanine." Journal of the American Chemical
Society, 111(18), 7205-9. (1989) PDF
- Sowers, Lawrence C.; Shaw, Barbara Ramsay; Sedwick, W.
David. Base stacking and molecular polarizability: effect
of a methyl group in the 5-position of pyrimidines.
Biochemical and Biophysical Research Communications (1987),
148(2), 790-4. PDF
- Chambers, Scott A. M.; Shaw, Barbara Ramsay. "Histone
modifications accompanying the onset of developmental
commitment." Developmental Biology, 124(2), 523-31.(1987) PDF
- Williams, Loren Dean; Chawla, B.; Shaw, Barbara Ramsay.
"The hydrogen bonding of cytosine with guanine: calorimetric and
proton NMR analysis of the molecular interactions of nucleic acid
bases." Biopolymers, 26(4), 591-603. (1987) PDF
- Williams, Loren Dean; Shaw, Barbara Ramsay. "Protonated
base pairs explain the ambiguous pairing properties of
O6-methylguanine." Proceedings of the National Academy of Sciences of
the United States of America, 84(7), 1779-83. (1987) PDF
- Sowers, Lawrence C.; Shaw, Barbara Ramsay; Veigl, Martina L.;
Sedwick, W. David. "DNA base modification: ionized base
pairs and mutagenesis." Mutation Research, 177(2), 201-18. (1987) PDF
- Chambers, Scott A. M.; Shaw, Barbara Ramsay. "Levels of
histone H4 diacetylation decrease dramatically during sea urchin
embryonic development and correlate with cell doubling rate." Journal
of Biological Chemistry, 259(21), 13458-63.(1984) PDF
- Chambers, Scott A. M.; Cognetti, Goffredo; Shaw, Barbara
Ramsay. "Diffusible factors are responsible for differences in
nuclease sensitivity among chromatins originating from different cell
types." Experimental Cell Research, 154(1), 213-23. (1984) PDF
- Richards, Randall G.; Shaw, Barbara Ramsay. "Temporal
changes in nucleosome populations during sea urchin early development."
Biochemistry, 23(9), 2095-102.(1984) PDF
- Mold, David E.; Weingart, Jon; Assaraf, Joel; Lubahn, Dennis B.;
Kelner, Drew N.; Shaw, Barbara Ramsay; McCarty, Kenneth S. Silver
staining of histones in Triton-acid-urea gels. Analytical
Biochemistry, 135(1), 44-7. (1983) PDF
- Chambers, Scott A. M.; Vaughn, James P.; Shaw, Barbara
Ramsay. "Shortest nucleosomal repeat lengths during sea urchin
development are found in two-cell embryos."
Biochemistry, 22(24), 5626-31. (1983) PDF
- Graham, Doyle G.; Anthony, D. Carter; Boekelheide, Kim;
Maschmann, Natalie A.; Richards, Randall G.; Wolfram, Joachim W.; Shaw,
Barbara Ramsay. "Studies of the molecular pathogenesis of hexane
neuropathy. II. Evidence that pyrrole derivatization of
lysyl residues leads to protein crosslinking." Toxicology and Applied
Pharmacology, 64(3), 415-22.(1982) PDF
- Richards, Randall G.; Shaw, Barbara Ramsay. "In situ
protamine release: a versatile sample preparation method for the
electrophoretic analysis of nuclear proteins on acid/urea-based gels."
Analytical Biochemistry, 121(1), 69-82. (1982) PDF
- Cognetti, Goffredo; Shaw, Barbara Ramsay. "Structural
differences in the chromatin from compartmentalized cells of the sea
urchin embryo: differential nuclease accessibility of micromere
chromatin." Nucleic Acids Research, 9(21), 5609-21. (1981) PDF
- Shaw, Barbara Ramsay; Cognetti, Goffredo; Sholes, William M.;
Richards, Randall G. "Shift in nucleosome populations during
embryogenesis: microheterogeneity in nucleosomes during
development of the sea urchin embryo." Biochemistry,
20(17), 4971-8. (1981) PDF
- Rill, Randolph L.; Shaw, Barbara Ramsay; Van Holde, Kensal
E. "Isolation and characterization of chromatin subunits."
Methods in Cell Biology, 18, 69-103. (1978)
- Shaw, Barbara Ramsay; Richards, Randall G.; Gross, Paul M.
"Preparation and analysis of core particles and nucleosomes: a
convenient method for studying the protein composition of nucleosomes
using protamine-release into triton-acid-urea gels." NATO Advanced
Study Institute Series, Series A: Life Sciences,
A21(Chromatic Struct. Funct., Part A), 125-36. (1979)
- Shaw, Barbara Ramsay; Schmitz, Kenneth S. "Conformation of
polynucleosomes in low ionic strength solution." NATO Advanced Study
Institute Series, Series A: Life Sciences, A21(Chromatic
Struct. Funct., Part B), 427-40. (1979)
- Schmitz, Kenneth S.; Shaw, Barbara Ramsay. "Hydrodynamic evidence
in support of spacer regions in chromatin."
Science, 197(4304), 661-3. (1977) PDF
- Van Holde, K. E.; Shaw, Barbara Ramsay; Tatchell, Kelly; Pardon,
John; Worcester, David; Wooley, John; Richards, Brian. The
structural subunit of chromatin. Mol. Biol. Mamm.
Genet. Appar. (1977), 1 239-54.
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