Event Information

Professor Gojko Lalic (Univ. of Washington, Dept. of Chemistry)
New Methods for Hydrofunctionalization of Unsaturated Compounds
Abstract:

Hydrofunctionalization reactions are some of the most desirable transformations of unsaturated compounds, and their development has been a major focus of research within the field of transition metal catalysis. Despite significant progress achieved over the years, control of regio- and stereoselectivity in hydrofunctionalization reactions remains a significant challenge. Recently, we have formulated general strategies for selective anti-Markovnikov hydrofunctionalization of alkenes and alkynes. Successful implementation of these strategies allowed us to develop new methods for anti-Markovnikov hydroamination of alkenes and semireduction of alkynes. In a related effort, we have explored stereospecific hydrofunctionalization of allenes as a general approach to asymmetric synthesis of hetero- and carbocyclic molecules containing quaternary stereocenters.

Host: Jiyong Hong

Thursday, September 19, 2013, 11:40am
Chemistry Seminar