Event Information
Characteristics of the Uhrig Dynamic Decoupling Sequence and Applications in Magnetic Resonance Imaging
- Abstract:
It has been theoretically demonstrated that the Uhrig Dynamic Decoupling (UDD) sequence1 provides better compensation for decoherence than the conventional Carr-Purcell-Meiboom-Gill (CPMG) sequence. This sequence has very promising applications in MRI; more specifically, it could be used to provide T2 extension and unique contrast2. Here we use theoretical simulations to explain distinctions between the UDD and CPMG sequences. Our results have shown that the UDD sequence is more sensitive to RF inhomogeneity but is more effective in suppressing low-frequency field fluctuations. Thus, the UDD sequence appears promising for extending T2. Experiments including water phantom and in vivo mouse imaging have also been conducted. Enhanced contrast in tumor tissue has been found using the UDD sequence with 16 refocusing pulses.
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