THE DEPARTMENT

Chairman                                                                         John D. Simon
                                                                                        101 Gross Chemical Laboratory

Director of Undergraduate Studies                                 James F. Bonk
                                                                                        222 Gross Chemical Laboratory

Associate Director of Undergraduate Studies                  Michael P. Montague-Smith
                                                                                        216 Gross Chemical Laboratory

Supervisor of Freshman Instruction                                Michael P. Montague-Smith
                                                                                         216 Gross Chemical Laboratory

Independent Study Coordinator                                      Michael P. Montague-Smith
                                                                                        216 Gross Chemical Laboratory

Undergraduate Career Coordinator                                 James F. Bonk
                                                                                        222 Gross Chemical Laboratory


The Chemistry Department consists of 19 full time faculty members plus one visiting professor, and one faculty member from another department who holds a secondary appointment in the Chemistry Department. All faculty members hold the Ph.D. degree and participate in undergraduate instruction including classroom teaching, undergraduate research, and advising. The following is a listing of the faculty (including recent emeriti) their office numbers, and the general area of their teaching and research. LSRC is Levine Science Research Center.

FACULTY

            S. W. Baldwin, Professor, Organic, Room 333
            D. Beratan, Professor, Physical, Room 377
            J. F. Bonk, Professor, Inorganic, Room 222
            S. L. Craig, Assistant Professor, Room 310
            A. L. Crumbliss, Professor, Inorganic, Room 312
            M. C. Fitzgerald, Assistant Professor, Analytical, Room 376
            M. W. Grinstaff, Assistant Professor, Inorganic, Room 330
            J. Liu, Assistant Professor, Physical Chemistry, Room 332
            C. H. Lochmüller, Professor, Analytical, Room 326
            R. A. MacPhail, Associate Professor, Physical, Room 308
            L. B. McGown, Professor, Analytical, Room 328
            A. T. McPhail, Professor, Physical, Room 336
            R. A. Palmer, Professor, Inorganic, Room 311
            M. C. Pirrung, Professor, Organic, LSRC Room B120
            B. R. Shaw, Professor, Biophysical, Room 335
            J. D. Simon, Chairman and George B. Geller Professor, Physical, Room 101
            E. J. Toone, Associate Professor, Organic, LSRC Room B120
            R. A. Widenhoefer, Assistant Professor, Organic, Room 376
            W. Yang, Professor, Physical, Room 373
 
 

SECONDARY-APPOINTMENT FACULTY

            T. G. Oas, Associate Professor, Biochemistry, 156 Nanaline Duke Bldg.
 
 

VISITING FACULTY

            J. F. Klein, Visiting Assistant Professor, Room 214
 
 

LECTURERS

            M. P. Montague-Smith, Associate Director of Undergraduate Studies, Room 216
             T. Woerner, Laboratory Manager, Room 220
 
 

INSTRUCTOR

            C. P. Roy, Laboratory Manager, Room 213
 
 

EMERITI FACULTY

            E. M. Arnett, R. J. Reynolds Professor Emeritus, Organic, Room 238
            D. B. Chesnut, Professor Emeritus, Physical, Room 309
            R. W. Henkens, Associate Professor Emeritus, Physical, Room TBA
            P. Smith, Professor Emeritus, Physical, Room 327
            H. A. Strobel, Professor Emeritus, Analytical, Room 218
            R. L. Wells, Professor, Inorganic, Room 356
            P. Wilder, Jr., University Distinguished Service Professor Emeritus, Organic, Room 353



COURSES OF INSTRUCTION

19 General Chemistry Credit. Pre-matriculation credit awarded on the basis of national/
 international examinations in chemistry such as College Board, International Baccalaureate,
 British Advanced Level. Depending on examination performance, placement may be for
 Chemistry 22L, 23L, or 151L. One course.

83 Chemistry, Technology, and Society. Science, the scientific method, and background topics from chemistry, biochemistry, and environmental chemistry that enable citizens to utilize the inductive-deductive methodology of science to better evaluate the potential benefits and risks associated with selected existing and proposed technologies. Intended primarily for non-majors. One course. Staff.

CORE COURSES
The following courses are usually required of all chemistry majors, regardless of degree program (B.S. or A.B.) or specialization program.

21L General Chemistry Emphasizes stoichiometry and atomic and molecular structure, with emphasis on applications to related fields such as biology and materials science. Laboratory work includes both qualitative and quantitative analysis. Prerequisite: one year of high school chemistry, a score of 610 on the Mathematics SAT or its equivalent, or consent of the supervisor of first-year instruction. Instructor: Staff. One course.

22L General Chemistry Emphasizes thermodynamics, chemical kinetics and equilibrium with emphasis on applications to related field such as biology and materials science. Laboratory work includes both qualitative and quantitative analysis. Prerequisite: Chemistry 21L or consent of the supervisor of first-year instruction. Instructor: Staff. One course.

23L Accelerated General Chemistry. An intensive introductory course for well-prepared students, covering in one semester the major topics of Chemistry 21L and 22L. Laboratory work includes both qualitative and quantitative analysis. Students may receive credit for only one of the following: Chemistry 22L or Chemistry 23L . Prerequisites: Score of 3, 4, or 5 on the Chemistry Advanced Placement Examination or a satisfactory score on a Duke administered chemistry placement examination. One course. Grinstaff or Crumbliss and staff.

151L, 152L. Organic Chemistry. The structures and reactions of the compounds of carbon. Laboratory: techniques of separation, organic reactions and preparation, and systematic identification of compounds by their spectral and chemical properties. Three lectures and one four-hour laboratory. Pre-requisite: Chemistry 19, 22L, or 23L, or the consent of the Director of Undergraduate Studies. Chemistry 151L is a prerequisite for 152L. Two courses. Baldwin, Craig, Pirrung, Toone or Widenhoefer.

161 Elements of Physical Chemistry. Survey of physical chemistry including quantum  chemistry, molecular structure, molecular spectroscopy, thermodynamics and kinetics.
 Three lectures. Corequisite: Chemistry 163L. Prerequisites: Chemistry 22L (or 23L or 19), Physics 52L(or 54L), and Mathematics 32L. With permission of instructor, Physics prerequisites may be taken as corequisites. Courses transferred as Phy 888 may also be acceptable (see page 7). One course. D. Beratan, J. Liu, R. MacPhail, McPhail, Simon,
or Yang.

163L Physical Chemistry Laboratory. Laboratory experiments designed to accompany Chemistry 161. Prerequisite (or co-requisite): Chemistry 161. Half course. Staff.

165, 166. Physical Chemistry. Fundamentals of physical chemistry. 165: emphasizes quantum chemistry, molecular structure, and molecular spectroscopy. 166: emphasizes
 thermodynamics and kinetics. Chemistry 167L should be taken concurrently with Chemistry 165. Chemistry 168L should be taken concurrently with Chemistry 166.
 Prerequisites for Chemistry 165 (or 23L or 19), Physics 52L(or 54L), and Mathematics 32L. Chemistry 165 (or permission of instructor) is a prerequisite for
 Chemistry 166. With permission of instructor, Physics prerequisites may be taken as corequisites. Courses transferred as Phy 888 may also be acceptable (see page 7).
 One course. D. Beratan, J. Liu, R. MacPhail, A. McPhail, Simon, or Yang.

167L, 168L. Physical Chemistry Laboratory. Laboratory experiments designed to accompany Chemistry 165, 166; respectively. Prerequisite (or corequisite): Chemistry 165 for 167L and 166 for 168L. Half course. Staff.

131 Analytical Chemistry. Fundamentals of qualitative and quantitative measurement with emphasis on chemometrics, quantitative spectrometry, electrochemical methods, and common separation techniques. Corequisite: Chemistry 133L. Prerequisite: Chemistry 163L, or 167L or 168L. One course. Fitzgerald, Lochmüller, or McGown.
133L Analytical Chemistry Laboratory. Laboratory experiments designed to accompany Chemistry 131. Prerequisite (or corequisite): Chemistry 131. Half course. Staff
 

ADVANCED COURSES
110 Chemical Information Retrieval. Techniques for manual and on-line searching of the major sources of chemical information, and their application to writing a review article. Half- course. Staff.

117 Inorganic Chemistry. Bonding, structure, and reactions of inorganic compounds studied through physical chemical concepts. Three lectures. Prerequisite: Chemistry 161, 165 or 166.  One course. Crumbliss, Grinstaff, McPhail, Palmer, or Wells.

157 Organic Synthesis. The reactions of organic synthesis including carbon-carbon bond formation and functional group transformations. Prerequisite: Chemistry 152L. One
 course. Staff.

158 Physical Organic Chemistry. Organic reaction mechanisms including fundamental techniques and specific mechanistic classes. Prerequisites: Chemistry 152L and one
 semester of physical chemistry. One course. Staff.

175 Molecular Basis of Biological Processes. Chemistry of the constituents of proteins, lipids, carbohydrates, and nucleic acids and their metabolic interrelationships. Prerequisite: Chemistry 152L and Biology 25L. Instructor: One course. Staff.

176 Biophysical Chemistry.
The physical chemical principles of and experimental methods employed in the study of biological macromolecules. Students may not receive credit for both Chemistry 176 and
196S. Prerequisites: Chemistry 161 and Biochemistry 227 (or Chemistry 175). One Course. Shaw, MacPhail.

180L Advanced Laboratory Techniques.
Synthesis of less common substances by techniques such as high or low pressure, high or low temperature, and/or inert atmospheres. Characterization of products from measure- ments such as electrical conductance, optical rotation, ultraviolet-visible spectra, infrared spectra, and/or mass spectra. Prerequisite (or corequisite): Chemistry 117. Half course. Staff.

275, 276. Advanced Studies.
(1) Analytical chemistry; (2) inorganic chemistry; (3) organic chemistry; and (4) physical chemistry. Open to especially well-prepared undergraduates by consent of the Director of Undergraduate Studies. Three lectures. One course each. Staff.


SMALL GROUP LEARNING EXPERIENCES
The following courses may be used to satisfy the College's requirement of small group learning experiences, while simultaneously satisfying certain requirements for the major in Chemistry.

26S Introduction to Research in Chemistry. (Coded NS, EI and R in Curriculum 2000)
Several weeks of active participation in a chemistry (or chemistry related) research group along with seminar classes in which research activities are discussed. Prerequisite: Chemistry 21L or 19. One course. Staff.

191, 192. Independent Study.
Supervised reading and research. Open to advanced students with the consent of the Independent Study Coordinator. For further information, see the discussion of Independent Study on page 25. One course each. Staff.

195S Seminar. (Coded NS and W in Curriculum 2000)
Howard Hughes Seminar for students engaged in independent study in chemistry or chemistry-related areas. Includes case studies of ethical issues in chemistry and instruction in writing a research proposal. One course. Staff.

196S Seminar.
Selected topics in physical chemistry of biological macromolecules. Students may not receive credit for both Chemistry 176 and 196S. Prerequisites: Chemistry 161 and Biochemistry 227 (or Chemistry 175). One course. Shaw.

198S. Seminar.
Topics from various areas of chemistry, changing each year. For example: organic chemistry of biologically important compounds, chemical basis of pharmacology, metal ions in biological systems. Open to senior chemistry majors or by consent of instructor. One course each. Staff.


 

FREQUENCY OF COURSE OFFERINGS, 2000-2001

The following tabulation of course offerings and prerequisites is presented to aid the student in planning a course of study.

Course      Prerequisite                                                                 Fall          Spring      SS I      SS II

21L               1 yr H.S. Chem, Mth SAT > 600                                    X                                  X
22L               CHEM 21L or 19                                                                              X                              X
23L               CHEM 19 or AP Score of 3                                           X
26S               CHEM 19 or 21L                                                                              X
83                 None                                                                                                  X
110               CHEM 22L, 23L, or 19                                          Not offered
117               CHEM 161/163L or 165/167L                                                          X
131               CHEM 161/163L or 165/167L                                        X
133L             CHEM 131 (Co- or pre-requisite)                                   X               X
151L             CHEM 22L, 23L, or 19                                                   X                                  X
152L             CHEM 151L                                                                                     X                               X
157               CHEM 152L                                                          Not offered
158               CHEM 152L, CHEM 161 or 165                          Not offered
161/163L      CHEM 22L, 23L, or 19; MTH 32L; PHY 52L*             X
165/167L      CHEM 22L, 23L, or 19: MTH 32L ; PHY 52L*            X
166/168L      CHEM 165                                                                                       X
175               CHEM 152L, BIO 25L                                                                                        X
176               CHEM 161, BCH 227 (OR CHEM 175)                                         X
180L             CHEM 117 (Co- or pre-requisite)                                                    X
191-2            Consent of DUS                                                            X                X                 X            X
195S,198S    Consent of Instructor                                                     X                X
275               Consent of DUS                                                            X
276               Consent of DUS                                                                               X
 
 

* PHY 52L may be replaced by PHY 54L.


REQUIREMENTS FOR A CHEMISTRY MAJOR

General statement concerning the transfer of physics courses.
Course(s) transferred as Phy 888 may be substituted for required physics courses: Physics 51L, 52L, 53L, or 54L, in either the A.B. or B.S. chemistry major, provided the physics course(s) are (1) calculus-based, (2) taken at an institution that is accredited by the American Chemical Society, and (3) are the courses which are required for an ACS-certified degree at that institution.


B.S. DEGREE IN CHEMISTRY

The B.S. degree program, accredited by the American Chemical Society, is recommended for students planning to undertake graduate study in Chemistry or a related science (e.g. biochemistry or pharmacology) or for those contemplating employment in the chemical industry following graduation. See work sheet version on pages 11 and 12.

            Prerequisites and Corequisites:                         MajorRequirements:
            Chem 21L and 22L; or 23L; or 19                      151L, 152L
            Mth 31L and 32L (or 41)                                    165/167L, 166/168L
            Phys 51L (or 53L) and 52L (or 54L)                  117, 131/133L
                                                                                        180L*

Plus three additional courses selected according to one of the following four options. Note that only options 1 and 2 are certified by the American Chemical Society.

Option 1. Certified by the American Chemical Society.
Biochemistry 227 (or Chemistry 175).
Plus two courses of independent study: Chemistry 191, 192 or 2 approved independent study courses in a science department in Trinity College, the Medical School, the Nicholas School of the Environment, or the Pratt School of Engineering.

Option 2. Certified by the American Chemical Society.
Biochemistry 227 (or Chem 175).
Plus one of the following: Chemistry 157,158,176,195S,196S,198S, 275 or 276.
Plus one course of independent study: Chemistry 191 or an approved independent study course in a science department in Trinity College, the Medical School, the Nicholas School of the Environment, or the Pratt School of Engineering.

Option 3. Not certified by the American Chemical Society.
One of the following: Chemistry 157, 158, 176, 195S, 196S, 198S, 275 or 276.
Plus two courses of independent study: Chemistry 191, 192 or 2 approved independent study courses in a science department in Trinity College, the Medical School, the Nicholas School of the Environment, or the Pratt School of Engineering.

Option 4. Not certified by the American Chemical Society.
At least 1 of the following: Chemistry 191 or 192.
Plus 1 (or 0) of the following: Chemistry 157,158,176,195S,196S,198S, 275 or 276.
Plus one approved advanced lecture course in a science department in Trinity College, the Medical School, the Nicholas School of the Environment, or the Pratt School of Engineering.

Recommendations:
Mathematics 103, 104 and Physics 100. Students planning graduate study in chemistry should consult with advisors regarding appropriate additional courses.

__________________
*Chem 180L is REQUIRED in all of the options for the B.S. Degree in Chemistry (without concentrations).


B.S. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN BIOCHEMISTRY

In conjunction with the Department of Biochemistry in the Duke Medical Center, the Chemistry Department is pleased to offer the B.S. degree in Chemistry with Concentration in Biochemistry. This program has proven to be very popular among students pursuing the Health Professions. Official recognition of the completion of the requirements given below occurs on the permanent transcript of a major. (See work sheet version on page 14.)

            Prerequisites:
            Chem 21L and 22L; or 23L; or 19;

            Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);Biology 25L.

            Major Requirements:
            Chemistry 117, 131/133L, 151L, 152L, 161 (or 165*) 163L (or 167L); 176 (or 166*)
            Biochemistry 227 (or Chemistry 175), 228; Biology 118, 119, plus one of the following:
            Chemistry 191, Biology 191, or Biochemistry 210.

            Recommendations:
            Mth 103, Chemistry 180L*, 192, 195S, 198S; Biology 184L, 192; advanced courses in Biochemistry.

________________
*Majors who wish to earn a B.S. degree in chemistry that is certified by the American Chemical Society must include Chem 165, 167L, 166, 168L, and 180L.


B.S. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN PHARMACOLOGY

In conjunction with the Department of Pharmacology in the Duke Medical Center, the Chemistry Department offers the B.S. degree in Chemistry with a Concentration in Pharmacology. Certification of the Concentration is designated on the official transcript. (See page 15 for a worksheet version.)

Pharmacology is more than the study of the mode of action of drugs. It is a science which uses the basic concepts of biology and chemistry to determine how drugs affect the organism; it gives a unique perspective in understanding how cells, organ systems, and organisms function. Unlike other basic science fields, pharmacology combines many disciplines so that one can investigate systematically the mechanisms underlying a biological event--from the molecular level to the whole animal. Pharmacology also allows us to study how biological systems fail, providing information on the etiology of disease and on the mechanisms underlying toxic reactions. Pharmacologic research is essential for the development, testing and use of drugs and other bioactive molecules such as pesticides or industrial chemicals.

The objective of Pharmacology as an Area of Concentration for Chemistry Majors is to provide students with knowledge of the basic principles underlying the design and actions of drugs and toxic substances. In addition, it provides the opportunity to apply these principles in a research setting. Ultimately, an introduction of pharmacology to undergraduates will encourage interested students to consider graduate study in the fields of pharmacology and/or medicinal chemistry, leading to a career in academic research, in governmental regulatory agencies, or in industry.

This area of concentration requires that students take specific courses in biological sciences and chemistry in addition to pharmacology, and two semesters of research in Pharmacology. The required courses are Biology 25L (Principles of Biology) and Biochemistry 227 (Introductory Biochemistry) (or Chemistry 175), which will provide the necessary biological background for Chemistry majors to proceed with studies in Pharmacology. Pharmacology 150 deals with drug actions and reactions. Pharmacology 233, Essentials of Pharmacology and Toxicology, is an entry-level, graduate course that uses mathematical, chemical, and biochemical principles to describe the mechanism of chemical interactions with biological targets (organs, receptors, enzymes, genomic processes). Students will also spend 2 semesters of independent study. Mentors for independent study are chosen from a list of approved pharmacology faculty. Other recommended pharmacology courses include an introductory course on the general aspects of the mode of drug action, Pharmacology: a course on Drugs, Brain and Behavior (Pharmacology 160); and a course in Mammalian Toxicology (Pharmacology 254).

            Prerequisites:
            Chem 21L and 22L; or 23L; or 19;
            Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);
            Biology 25L, Biochemistry 227 (or Chemistry 175).

            Major Requirements:
            Chemistry 117, 131/133L, 151L, 152L, 161 (or 165*); 163L (or 167L); 176 (or 166*)
            plus Pharmacology 150, 233;
           plus 2 semesters of independent study (Chemistry
                   191**, 192** or Pharmacology 191, 192).

           Recommendations.
           Mth 103, Chemistry 180L*, Biology 151L, Pharmacology 160, 234, and 254.
 

*Majors who wish to earn a B.S. degree in chemistry that is certified by the American Chemical Society must include Chem 165, 167L, 166, 168L, and 180L.

________________
**The independent study project must involve some aspect of pharmacology.


B.S. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN ENVIRONMENTAL CHEMISTRY

In conjunction with the School for the Environment of Duke University the Chemistry Department is pleased to offer the B.S. degree in Chemistry with Concentration in Environmental Chemistry. Official recognition of the completion of the requirements given below will appear on the permanent transcript of a major. (See work sheet version on page 16.)

           Prerequisites:
            Chem 21L and 22L; or 23L; or 19;
            Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);
           plus two of the following: Biology 25L, Biology 118, Earth and Ocean Sciences 41, 120.

            Major Requirements:
            Chemistry 117, 131/133L, 151L, 152L, 161 (or 165*); 163L (or 167L); 176 (or 166*);
            Any two of the following: Environment 240, 241, 242;
           plus one of the following: Chemistry 191**, Environment 191.

            Recommendations:
            Chemistry 180L*, 192, 195S, 198S; Math 103, Biology 110L, Environment 192, 243,
            298.02 or Earth and Ocean Sciences 272.
 

*Majors who wish to earn a B.S. degree in chemistry that is certified by the American Chemical Society must include Chemistry 165, 167L, 166, 168L, and 180L and Biochemistry 227 (or Chemistry 175).

_________________
**The independent study project must involve some aspect of environmental chemistry.

SEQUENCE OF COURSES FOR THE B.S. DEGREE IN CHEMISTRY

The following is a typical schedule for the core and prerequisite courses for a student who is seeking the B.S. degree and does not having advanced placement credits in Chem or Mth. The remaining advanced courses are chosen from those listed on pages 7-9 in the section entitled Major Requirements. (Symbols are as follows: [ ] represents prerequisite course required for the degree.

                                                    Fall                                           Spring

                            Fr                     CHEM 21L                                CHEM 22L
                                                     [MTH 31L]                               [MTH 32]
                                                                                                       [PHY 51L]*

                            So                     CHEM 151L                             CHEM 152L
                                                     [PHY 52L]*

                            Jr                      CHEM 165/167L                      CHEM 166/168L

                            Sr                     CHEM 131/133L                      CHEM 117
                                                                                                       CHEM 180L

_______________
 *PHY 51L(Spring)-52L(Fall) may be replaced by PHY 53L(Fall)-54L(Spring).
 

Note: Chemistry 165/167L is a prerequisite for most upper level chemistry course and usually taken in the junior year. Since Physics 52L(or 54L) is prerequisite for Chemistry 165, Physics is normally taken in the sophomore year and Mathematics 31L and 32L in the freshman year. With permission of the course instructor, however, a physics course and Chemistry 165 may be taken concurrently.

Physics and Math courses may be taken at other times, but only with some loss of flexibility in scheduling.


Work Sheet for BS Major in Chemistry
(2001 Revision)

Name __________________________________________ Advisor_______________________

Indicate semester and year (SYR) in which you plan to take courses. In the SYR notation, S = number indicating the semester (1 = spring, 2 = summer, and 5 = fall); and YR is a number consisting of the last two digits of the year. For example, 599 would be used for fall semester of 1999. Circle "fulfilled" when a requirement to its left has been completed. Circle the option which is being followed to complete the major.

Prerequisites:

                   OR: CHEM 21L ____     AND CHEM 22L ____ ;

                   OR: CHEM 23L ____     OR     CHEM 19 ____                                                  Fulfilled
 

                AND: MTH 31L (or 31)____     AND MTH 32L (or 32)____

                   OR: MTH 41 ____                                                                                                Fulfilled
 

                AND:         PHY 51L ____     AND PHY 52L ____

                   OR:         PHY 53L ____     AND PHY 54L ____                                                Fulfilled
 

Major Requirements:

           Core Courses:

                           CHEM 151L ____     AND CHEM 152L ____ Fulfilled

                AND: CHEM 165/167L ___/___     AND CHEM 166/168L ___/___                     Fulfilled

                AND: AND 131/133L ___/___                                                                                 Fulfilled

                AND: CHEM 117 ____     AND CHEM 180L* ____                                             Fulfilled
 

*Chem 180L is REQUIRED in all options for the B.S. Degree in Chemistry without a concentration.
 

Option 1. Certified by the American Chemical Society.

                BCH 227 ____     OR     CHEM 175 ____                                                              Fulfilled

                Plus 2 courses in independent study:

                            CHEM 191 ____, CHEM 192 ____

                            OR: 2 approved independent study courses in a
                            science department in Trinity College, the Medical School,
                            Nicholas School of the Environment, or the Pratt School
                                    of Engineering.
                            List the Department, Course Numbers, and grades.

                            ________ ______ ______,

                            ________ ______ ______,                                                                           Fulfilled
 

Option 2. Certified by the American Chemical Society.

                BCH 227_____ OR     CHEM 175 ____                                                                 Fulfilled

                Plus one of the following:

                            CHEM 157 ____     CHEM 158 ____ CHEM 176 ____,

                            CHEM 195S ____,     CHEM 196S ____,     CHEM 198S ____,

                            CHEM 275 ____,     CHEM 276 ____.                                                        Fulfilled

                Plus 1 course in independent study:

                            CHEM 191 ____,

                            OR: an approved independent study course in a
                            science department in Trinity College, the Medical School,
                            Nicholas School of the Environment, or the Pratt School
                                    of Engineering.
                            List the Department, Course Number, and grade.

                             ________ ______ ______,                                                                          Fulfilled
 

Option 3. Not certified by the American Chemical Society.

                One of the following:

                            CHEM 157 ____     CHEM 158 ____     CHEM 176 ____,

                            CHEM 195S ____,     CHEM 196S ____,     CHEM 198S ____,

                            CHEM 275 ____,     CHEM 276 ____.                                                        Fulfilled

                 Plus 2 courses in independent study:

                            CHEM 191 ____,     CHEM 192 ____,

                            OR: 2 approved independent study courses in a
                            science department in Trinity College, the Medical School,
                            Nicholas School of the Environment, or the Pratt School
                                    of Engineering.
                            List the Department, Course Numbers, and grades.

                            ________ ______ ______,

                            ________ ______ ______,                                                                          Fulfilled
 

Option 4. Not certified by the American Chemical Society.

                At least one of the following:

                            CHEM 191 ____,     CHEM 192 ____                                                        Fulfilled

                Plus one (or 0) of the following:

                            CHEM 157 ____     CHEM 158 ____     CHEM 176 ____,

                            CHEM 195S ____,     CHEM 196S ____,     CHEM 198S ____,

                            CHEM 275 ____,     CHEM 276 ____.                                                        Fulfilled

                Plus 1 approved advanced lecture course in a science
                department in Trinity College, the Medical School,
                the Nicholas School of the Environment, or the Pratt School
                        of Engineering.
                List the Department, Course Number, and grade.

                 ________ ______ ______,                                                                                     Fulfilled
 
 

Work Sheet for BS Major in Chemistry
with Concentration in Biochemistry
(2001 Revision)

Name __________________________________________ Advisor_______________________

Indicate semester and year (SYR) in which you plan to take courses. In the SYR notation, S = number indicating the semester (1 = spring, 2 = summer, and 5 = fall); and YR is a number consisting of the last two digits of the year. For example, 599 would be used for fall semester of 1999. Circle "fulfilled" when a requirement to its left has been completed. Circle the option which is being followed to complete the major.

Prerequisites:

                       CHEM 21L ____ AND     CHEM 22L ____ ;

                OR CHEM 23L ____     OR     CHEM 19 ____                                                      Fulfilled

                AND: MTH 31L____     AND MTH 32L____

                   OR: MTH 41 ____                                                                                                Fulfilled

                AND: PHY 51L ____     AND PHY 52L ____

                   OR: PHY 53L ____     AND PHY 54L ____                                                         Fulfilled

                AND: BIO 25L ____                                                                                                Fulfilled
 

Major Requirements:

           Core Courses:

                           CHEM 151L ____     AND CHEM 152L ____                                            Fulfilled

                AND: CHEM 161/163L ____/_____     OR     CHEM 165*/167L*____/____      Fulfilled

                AND: CHEM 176 ____     OR     CHEM 166* ____                                              Fulfilled

                AND: CHEM 117* ____     AND CHEM 131/133L ____/____                            Fulfilled

                AND: BCH 227     (OR CHEM 175) ____     AND BCH 228 ____                      Fulfilled

                AND: BIO 118 ____     AND BIO 119 ____                                                          Fulfilled

                AND AT LEAST ONE OF THE FOLLOWING:

                          CHEM 191 ____     OR BIO 191 ____     OR     BCH 210 ____                 Fulfilled
 

Recommended: CHEM 180L* _____;                                                                                  Fulfilled

                            CHEM 192 _____,     CHEM 195S _____

                            BIO 184L _____,     BIO 192 _____
                            (advanced courses in biochemistry)
 
 

*To earn a B.S. degree in Chemistry certified by the American Chemical Society requires Chemistry 165, 166, 167L, 168L, and 180L (which has a Chemistry 117 co- or pre-requisite).
 
 

Work Sheet for BS Major in Chemistry
with Concentration in Pharmacology
(2001 Revision)

Name __________________________________________ Advisor_______________________

For completed courses, indicate grades on blanks. Circle "fulfilled" when the requirement to its left has been completed.

For remaining requirements, indicate the semester and year (SYR) in which you plan to take courses. In the SYR notation, S = number indicating the semester (1 = spring, 2 = summer, and 5 = fall); and YR is a number consisting of the last two digits of the year. For example, 199 would be used for spring semester of 1999.

Prerequisites:

                           CHEM 21L ____     AND CHEM 22L ____ ;

                   OR: CHEM 23L ____     OR     CHEM 19 ____                                                  Fulfilled

                AND: MTH 31L ____     AND MTH 32L ____

                   OR: MTH 41 ____                                                                                                Fulfilled

                AND: PHY 51L ____     AND PHY 52L ____

                   OR: PHY 53L ____     AND PHY 54L ____                                                        Fulfilled

                AND: BIO 25L ____                                                                                               Fulfilled

                AND: BCH 227 ____     OR     CHEM 175 ____                                                   Fulfilled
 

Major Requirements:

                            CHEM 151L ____     AND CHEM 152L ____                                           Fulfilled

                 AND: CHEM 161/163L ___/___     OR     CHEM 165*/167*L ____/____          Fulfilled

                 AND: CHEM 176 ____     OR     CHEM 166* ____                                             Fulfilled

                 AND: CHEM 131/133L ___/___     AND CHEM 117 ____                                  Fulfilled

                 AND: PHR 150 ____     PHR 233 ____                                                                 Fulfilled

                 AND: TWO OF THE FOLLOWING:

                            CHEM 191 ___     CHEM 192____     PHR 191____     PHR 192____    Fulfilled
 

Recommended: CHEM 180L*____                                                                                      Fulfilled

                             and MTH 103, BIO 151L, PHR 160, 234, and 254.
 

*To earn a B.S. degree in Chemistry certified by the American Chemical Society requires Chemistry 165, 166, 167L, 168L, and 180L (which has a Chemistry 117 co- or pre-requisite).
 
 

Work Sheet for BS Major in Chemistry
with Concentration in Environmental Chemistry
(2001 Revision)

Name __________________________________________ Advisor_______________________

Indicate the semester and year (SYR) in which you plan to take courses. In the SYR notation, S = number indicating the semester (1 = spring, 2 = summer, and 5 = fall); and YR is a number consisting of the last two digits of the year. For example, 599 would be used for fall semester of 1999.

Prerequisites:

                           CHEM 21L ____     AND CHEM 22L ____ ;

                   OR: CHEM 23L ____     OR     CHEM 19 ____                                                  Fulfilled

                AND: MTH 31L____     AND MTH 32L____ ,

                   OR: MTH 41 ____                                                                                                Fulfilled

                AND: PHY 51L ____    AND PHY 52L ____

                   OR: PHY 53L ____     AND PHY 54L ____                                                        Fulfilled

                AND AT LEAST TWO OF THE FOLLOWING:

                        BIO 25L ____

                        EOS 41 ____    EOS 120 ____                                                                        Fulfilled
 

Major Requirements:

           Core Courses:

                            CHEM 151L ____     AND CHEM 152L ____                                           Fulfilled

                 AND: CHEM 161/163L ___/___     OR     CHEM 165*/167L* ____/____         Fulfilled

                 AND: CHEM 176 ____     OR     CHEM 166* ____                                            Fulfilled

                 AND: CHEM 117 ____     AND     CHEM 131/133L ____/____                         Fulfilled

                 AND TWO OF THE FOLLOWING:

                           ENV 241 ____     ENV 240 ____     OR     ENV 242 ____                         Fulfilled

                 AND: CHEM 191** ____     OR     ENV 191 ____                                             Fulfilled
 

Recommended: CHEM 180L* _______;                                                                             Fulfilled

                            OTHERS: CHEM 192, 195S, 198S, BIO 110L,
                            ENV 192, 243, 298.02, MTH 103, Earth and Ocean Sciences 272
 
 

* To earn a B.S. degree in Chemistry certified by the American Chemical Society requires Chemistry 165, 166, 167L, 168L, and 180L (which has a Chemistry 117 co- or pre-requisite); and Biochemistry 227 (or Chemistry 175).

_______________
**Project must involve some aspect of environmental chemistry.


A.B. DEGREE IN CHEMISTRY

The A.B. degree program allows greater flexibility in scheduling and course selection, while still maintaining the integrity of the Chemistry major. Students with interests in a second under-graduate major or in advanced work in a professional school (e.g. medical, dental, veterinary, business, or law) following graduation should consider this program. Students with an interest in employment in the chemical or a related industry, or in advanced study in chemistry or a related science (e.g. biochemistry or pharmacology) may also consider this program, although they are encouraged to augment their program with additional upper-level chemistry courses. Students in this category should consult their faculty advisers early in their junior year. See work sheet versions on pages 19 and 20.
 

                Prerequisites:
                Chem 21L and 22L; or 23L; or 19; Mathematics 31L, 32L (or 41); Physics 51L, 52L (or 53L-54L).
 

                Major Requirements:
                Chemistry 131, 133L, 151L, 152L, 161 (or 165, 166), 163L (or 167L), plus one of the following options:

                1.     Three of the following: Chemistry 117, 157, 158, 166L, 176, 195S, 196S, 198S,
                        Biochemistry 227 (or Chemistry 175), 228.
                2.     One of the following: Chemistry 117, 157, 158, 166, 176, Biochemistry 227
                        (or Chemistry 175); plus Chemistry 191, 192 or the equivalent in a natural science,
                        mathematics, engineering, or a basic science department in the School of Medicine.
                3.     One of the following:
                        a.  Physics Emphasis
                            Chemistry 166 (or 176) plus any 2 of the following**:
                            Physics 143 Optic and Modern Physics (Prereq: Phy 51L, 52L;
                            Mathematics 103)
                            Physics 181 Introductory Mechanics (Prereq: Phy 51L, 52L;
                            Mathematics 103, 111 or eq.)
                            Physics 182 Electricity and Magnetism (Prereq: Phy 51L, 52L,
                            Mathematics 103, 111, or eq.)
                        b. Mathematics Emphasis
                            Chemistry 166 (or 176) plus any 2 of the following**:
                            Mathematics 111 Applied Mathematical Analysis I (Prereq: Math 103)
                            Mathematics 114 Applied Mathematical Analysis II (Prereq: Math 111).
                            Mathematics 131 Elementary Differential Equations (Prereq: Math 103:
                            coreq: Mathematics 104.)
                        c. Biology Emphasis
                            Biochemistry 227 (or Chem 175) plus any 2 of the following**:
                            Biology 151L Animal Physiology (Prereq: Bio 25L)
                            Biology 152 Plant Physiology (Prereq: Bio 25L; 1 yr of Chem; Org. chem. desirable)
                            Biology 118 Cell Biology and Genetics (Prereq: Bio 25L)
                            Biology 184L Experimental Cell and Molecular Biology (Prereq: Bio 118 or 119)
                            Biology 185L Development and Molecular Genetics (Instructor' permission)
                            Biology 244 Immunology (Prereq: Bio 119 and Chem 151L)
 

**Substitution may be made in certain cases with the permission of the Director of Undergraduate Studies.

Recommendations: CPS 6, or EGR 51, MTH 103, and CHEM 166 (or 176). Students planning graduate study are advised to take these recommended courses and to consult with advisers regarding appropriate additional courses.
 
 

A.B. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN BIOCHEMISTRY

In conjunction with the Department of Biochemistry in the Duke Medical Center, the Chemistry Department is pleased to offer the A.B. degree in Chemistry with Concentration in Biochemistry. This program has proven to be very popular among students pursuing the Health Professions. Official recognition of the completion of the requirements given below occurs on the permanent transcript of a major. (See work sheet version on page 22.)

                   Prerequisites:
                    Chem 21L and 22L; or 23L; or 19;
                    Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);
                    Biology 25L.

                    Major:
                    Chemistry 131/133L, 151L, 152L, 161 (or 165, 166), 163L (or 167L), Biochemistry 227
                    (or Chemistry 175), Biochemistry 228;
                   plus one of the following: Chemistry 157, 158, 166, 176, 191, 195S, 198S;
                    Biology 118, 184L, 185L, 191; or any advanced courses in Biochemistry.
 
 

A.B. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN PHARMACOLOGY

In conjunction with the Department of Pharmacology in the Duke Medical Center, the Chemistry Department offers the A.B. degree in Chemistry with a Concentration in Pharmacology. Certification of the Concentration is designated on the official transcript. (See work sheet version on page 23.)

Pharmacology is more than the study of the mode of action of drugs. It is a science which uses the basic concepts of biology and chemistry to determine how drugs affect the organism; it gives a unique perspective in understanding how cells, organ systems, and organisms function. Unlike other basic science fields, pharmacology combines many disciplines so that one can investigate systematically the mechanisms underlying a biological event--from the molecular level to the whole animal. Pharmacology also allows us to study how biological systems fail, providing information on the etiology of disease and on the mechanisms underlying toxic reactions. Pharmacologic research is essential for the development, testing and use of drugs and other bioactive molecules such as pesticides or industrial chemicals.

The objective of Pharmacology as an Area of Concentration for Chemistry Majors is to provide students with knowledge of the basic principles underlying the design and actions of drugs and toxic substances. In addition, it provides the opportunity to apply these principles in a research setting. Ultimately, an introduction of pharmacology to undergraduates will encourage interested students to consider graduate study in the fields of pharmacology and/or medicinal chemistry, leading to a career in academic research, in governmental regulatory agencies, or in industry.

                   Prerequisites:
                    Chem 21L and 22L; or 23L; or 19;
                    Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);
                    Biology 25L, Biochemistry 227 (or Chemistry 175).

                    Major:
                    Chemistry 131/133L, 151L, 152L, 161 (or 165, 166), 163L (or 167L);
                            Pharmacology 150 or 233;
                   plus 2 semesters of independent study involving some aspect of pharmacology (Chemistry 191, 192 or Pharmacology 191, 192).
 
 

A.B. DEGREE IN CHEMISTRY
WITH CONCENTRATION IN ENVIRONMENTAL CHEMISTRY

In conjunction with the School for the Environment of Duke University, the Chemistry Department is pleased to offer the A.B. degree in Chemistry with Concentration in Environmental Chemistry. Official recognition of the completion of the requirements given below will appear on the permanent transcript of a major. (See work sheet version on page 24.)

                   Prerequisites:
                    Chem 21L and 22L; or 23L; or 19;
                    Mathematics 31, 32 (or 31L, 32L or 41); Physics 51L, 52L (or 53L, 54L);
                   plus two of the following: Biology 25L, Biology 118L, Earth and Ocean Sciences 41, 120.

                    Major:
                    Chemistry 131,133L, 151L, 152L, 161 (or 165, 166), 163L (or 167L);
                   Plus two of the following: Environment 240, 241, 242;
                   Plus one of the following: Chemistry 117, 157, 158, 166, 176, 191*, 195S, 198S;
                            Biology 110L; Environment 191, 243, 298.02, or Earth and Ocean Sciences 272.
 

**The independent study project must involve some aspect of environmental chemistry.


SEQUENCE OF COURSES FOR THE A.B. DEGREE IN CHEMISTRY

The following is a typical schedule for the core and prerequisite courses for a student who does not have advanced placement credits for Chem or Mth and is seeking the A.B. degree. The additional courses listed in the various options above may be taken in the junior or senior year. Prerequisites for some of the options may need to be completed in the freshman or sophomore year. (Symbols are as follows: [ ] represents prerequisite course required for the degree.

                                                               Fall                                             Spring

                                  Fr                         CHEM 21L                                  CHEM 22L
                                                              [Math 31L]                                   [Math 32L]

                                  So                        CHEM 151L                                CHEM 152L
                                                              [Physics 53L]*                             [Physics 54L]*

                                 Jr                          CHEM 161/163L

                                 Sr                         CHEM 131/133L
 

*PHY 53L(Fall) - 54L(Spring) may be replaced by PHY 51L(Spring) - 52L(Fall).
 

Note: Chemistry 161/163L is a prerequisite for most upper level chemistry course and usually taken in the junior year. Since Physics 52L(or 54L) is prerequisite for Chemistry 161, Physics is normally taken in the sophomore year and Mathematics 31L and 32L in the freshman year. With permission of the course instructor, however, a physics course and Chemistry 161 may be taken concurrently.

Physics and Math courses may be taken at other times, but only with some loss of flexibility in scheduling.


Work Sheet for AB Major in Chemistry
(2001 Revision)

Name __________________________________________ Advisor_______________________

Indicate semester and year (SYR) in which you plan to take courses. In the SYR notation, S = number indicating the semester (1 = spring, 2 = summer, and 5 = fall); and YR is a number consisting of the two digits of the year. For example, 599 would be used for fall semester of 1999. Circle "fulfilled" when a requirement to its left has been completed. Circle the option which is being followed to complete the major.

Prerequisites:

                           CHEM 21L ____     AND CHEM 22L ____ ;

                   OR: CHEM 23L ____     OR     CHEM 19 ____                                                  Fulfilled

                AND: MTH 31L ____     AND MTH 32L ____

                   OR: MTH 41 ____                                                                                                Fulfilled

                AND: PHY 51L ____     AND PHY 52L ____

                   OR: PHY 53L ____     AND PHY 54L ____                                                        Fulfilled
 

Major Requirements:

Core Courses:

                           CHEM 151L ____     AND CHEM 152L ____                                            Fulfilled

                AND: CHEM 161/163L ___/___

                &nbs