Welcome
to the Home of Iron Chemistry at Duke.
. . We are the Real Iron Dukes.
Congratulations to Dr. Katherine Weaver for her Ph.D. defense on December
11, 2007!
Congratulations to former group member, Kassy Mies on her recent
appointment as Mary Elizabeth Yarborough Chair, Assistant Professor of
Chemistry at Meredith College in Raleigh, NC!
Some Recent
Publications
Bonaventura, Celia; Henkens,
Robert; Alayash, Abdu I.; Crumbliss, Alvin L.. Allosteric effects
on oxidative and nitrosative reactions of cell-free hemoglobins.
IUBMB Life (2007), 59(8-9), 498-505.
Anderson, Damon S.; Adhikari, Pratima; Weaver, Katherine D.;
Crumbliss, Alvin L.; Mietzner, Timothy A. The Haemophilus
influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease
and development of a gallium-based screen for mutants. Journal of
Bacteriology (2007), 189(14), 5130-5141.
Remington, Nicole; Stevens, Robert D.; Wells, Randall S.; Holn,
Aleta; Dhungana, Suraj; Taboy, Celine H.; Crumbliss, Alvin L.; Henkens,
Robert; Bonaventura, Celia. Genetic diversity of coastal bottlenose
dolphins revealed by structurally and functionally diverse hemoglobins.
Gene (2007), 398(1-2), 123-131.
Heymann, J. J.; Weaver, K. D.; Mietzner, T. A.; Crumbliss, A. L..
Sulfate as a Synergistic Anion Facilitating Iron Binding by the
Bacterial Transferrin FbpA: The Origins and Effects of Anion
Promiscuity. Journal of the American Chemical Society (2007),
129(31), 9704-9712.
Mies, Kassy A.; Wirgau, Joseph I.; Crumbliss, Alvin L.. Ternary
complex formation facilitates a redox mechanism for iron release from
a siderophore. BioMetals (2006), 19(2), 115-126.
Crumbliss Group, Spring 2006:
(left to right) [front] Richard Arriaga (Undergrad), Esther Tristani
(3rd year), Dr. Katherine Weaver (Graduated December 2007), Dr. Crumbliss, [back] James
Harrington (3rd year), Claire Parker Siburt (3rd year), Dr. Kassy Mies
(Graduated May 2007), Jared Heymann (5th year), Arnav Mehta (undergrad)
Recent
Presentations
Heymann, Jared J.; Weaver,
Katherine D.; Anderson, D. S.; Mietzner, T. A.; Crumbliss, A. L..
Biological trivalent metal selectivity in a bacterial transferrin:
Gallium-FbpA thermodynamics and kinetics. Abstracts of Papers,
234th ACS National Meeting, Boston, MA, United States, August 19-23,
2007 (2007), INOR-886.
Harrington, James M.; Crumbliss, A. L.; Dhungana, S.; Chittamuru,
S.; Jacobs, Hollie K.; Gopalan, A. S. Iron(III) sequestration by
synthetic hydroxypyridinone siderophores and exchange with
desferrioxamine B. Abstracts of Papers, 234th ACS National
Meeting, Boston, MA, United States, August 19-23, 2007 (2007),
INOR-816.
Heymann, Jared J.; Mietzner, T. A.; Crumbliss, A. L.. Effects
and origins of the synergistic anion influence on the thermodynamics
and kinetics of iron binding by a bacterial transferrin. Abstracts
of Papers, 232nd ACS National Meeting, San Francisco, CA, United
States, Sept. 10-14, 2006 (2006), INOR-610.
Upcoming
Publications & Presentations
Check out
Claire and Esther's talks at the New Orleans National ACS meeting this
spring!